Last updated: 2025-10-15

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Knit directory: CPLASS/

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CPLASS (Continuous Piecewise-Linear Approximation via Stochastic Search) is a computational framework for detecting changes in velocity within multidimensional time-series data. Unlike conventional changepoint detection algorithms that focus on mean shifts, CPLASS identifies changes in slope (velocity) while enforcing continuity constraints across segments — making it particularly suited for complex, continuous processes such as intracellular transport dynamics.

Authors: Linh Do, Scott A. McKinley, Keisha J. Cook.